Heavy Quark Spin Symmetry Violating Hadronic Transitions of Higher Charmonia

In heavy quarkonia, hadronic transitions serve as an enlightened probe for the structure and help to establish the understanding of light quark coupling with a heavy degree of freedom. Moreover, in recent years, hadronic transitions revealed remarkable discoveries to identify the new conventional heavy quarkonia and extracting useful information about the so called "XYZ" exotic states. In this contribution, we present our predictions for heavy quark spin symmetry (HQSS) breaking hadronic transitions of higher $S$ and $D$ wave vector charmonia based on our recently proposed model (inspired by Nambu-Jona-Lasinio (NJL) model) to create light meson(s) in heavy quarkonium transitions. We also suggest spectroscopic quantum numbers $(^{2S+1}L_J)$ for several observed charmoniumlike states. Our analysis indicates that the $Y(4360)$ is most likely to be a $3D$ dominant state.Comment: Proceedings of the talk presented at "XVII International Conference on Hadron Spectroscopy and Structure (Hadron2017)", 25-29 September 2017, Salamanca, Spai

χb(3P)\chi_{b}(3P) Multiplet Revisited: Ultrafine Mass Splitting and Radiative Transitions

Invoked by the recent CMS observation regarding candidates of the $\chi_b(3P)$ multiplet, we analyze the ultrafine and mass splittings among $3P$ multiplet in our unquenched quark model (UQM) studies. The mass difference of $\chi_{b2}$ and $\chi_{b1}$ in $3P$ multiplet measured by CMS collaboration ($10.6 \pm 0.64 \pm 0.17$ MeV) is very close to our theoretical prediction ($12$ MeV). Our corresponding mass splitting of $\chi_{b1}$ and $\chi_{b0}$ enables us to predict more precisely the mass of $\chi_{b0}(3P)$ to be ($10490\pm 3$) MeV. Moreover, we predict ratios of the radiative decays of $\chi_{bJ}(nP)$ candidates, both in UQM and quark potential model. Our predicted relative branching fraction of $\chi_{b0}(3P)\to\Upsilon(3S)\gamma$ is one order of magnitude smaller than $\chi_{b2}(3P)$, this naturally explains the non-observation of $\chi_{b0}(3P)$ in recent CMS search. We hope these results might provide useful references for forthcoming experimental searches

Multifunctional photonic integrated circuit for diverse microwave signal generation, transmission and processing

Microwave photonics (MWP) studies the interaction between microwave and optical waves for the generation, transmission and processing of microwave signals (i.e., three key domains), taking advantages of broad bandwidth and low loss offered by modern photonics. Integrated MWP using photonic integrated circuits (PICs) can reach a compact, reliable and green implementation. Most PICs, however, are recently developed to perform one or more functions restricted inside a single domain. In this paper, as highly desired, a multifunctional PIC is proposed to cover the three key domains. The PIC is fabricated on InP platform by monolithically integrating four laser diodes and two modulators. Using the multifunctional PIC, seven fundamental functions across microwave signal generation, transmission and processing are demonstrated experimentally. Outdoor field trials for electromagnetic environment surveillance along an in-service high-speed railway are also performed. The success to such a PIC marks a key step forward for practical and massive MWP implementations.Comment: 17 page

CXCR4 Antagonist AMD3100 Modulates Claudin Expression and Intestinal Barrier Function in Experimental Colitis

Ulcerative colitis is a gastrointestinal disorder characterized by local inflammation and impaired epithelial barrier. Previous studies demonstrated that CXC chemokine receptor 4 (CXCR4) antagonists could reduce colonic inflammation and mucosal damage in dextran sulfate sodium (DSS)-induced colitis. Whether CXCR4 antagonist has action on intestinal barrier and the possible mechanism, is largely undefined. In the present study, the experimental colitis was induced by administration of 5% DSS for 7 days, and CXCR4 antagonist AMD3100 was administered intraperitoneally once daily during the study period. For in vitro study, HT-29/B6 colonic cells were treated with cytokines or AMD3100 for 24 h until assay. DSS-induced colitis was characterized by morphologic changes in mice. In AMD3100-treated mice, epithelial destruction, inflammatory infiltration, and submucosal edema were markedly reduced, and the disease activity index was also significantly decreased. Increased intestinal permeability in DSS-induced colitis was also significantly reduced by AMD3100. The expressions of colonic claudin-1, claudin-3, claudin-5, claudin-7 and claudin-8 were markedly decreased after DSS administration, whereas colonic claudin-2 expression was significantly decreased. Treatment with AMD3100 prevented all these changes. However, AMD3100 had no influence on claudin-3, claudin-5, claudin-7 and claudin-8 expression in HT-29/B6 cells. Cytokines as TNF-α, IL-6, and IFN-γ increased apoptosis and monolayer permeability, inhibited the wound-healing and the claudin-3, claudin-7 and claudin-8 expression in HT-29/B6 cells. We suggest that AMD3100 acted on colonic claudin expression and intestinal barrier function, at least partly, in a cytokine-dependent pathway

Nicorandil alleviates inflammation and oxidation in diabetic cardiomyopathy

Purpose: To examine the effect of nicorandil on high glucose-induced cardiomyocyte inflammation and oxidative stress.Methods: H9C2 cardiomyocytes were divided into control group, high glucose group and nicorandil group. The survival rate of cardiomyocytes was determined using the CCK-8 method. The contents of reactive oxygen species (ROS) of cardiomyocytes were determined by flow cytometry. The contents of MDA and LDH in cell supernatant were determined by kit. Western blot and real-time PCR were used to assess oxidative stress, inflammation and apoptosis related factors in each group of cardiomyocytes. The expression levels of IL-1β were determined by immunofluorescence. Tunnel staining was used to determine the apoptosis level of each group.Results: The expressions of SOD1 and SOD2 in the high glucose group were significantly decreased (p < 0.05). Also, the contents of MDA and LDH were significantly increased (p < 0.05). Furthermore, IL-1β, TNF-α, caspase 3 and Bax expressions were increased, while Bcl-2 expression was inhibited. IL-1β and Tunnel fluorescence also increased significantly. NF-κB and Ikkα were significantly increased, while IκB-α was inhibited. Furthermore, nicorandil inhibited oxidative stress and apoptosis, as well as NF-κB pathway and downstream factor Ikkα.Conclusion: Nicorandil ameliorates the inflammation and oxidative damage of cardiomyocytes induced by high glucose, by inhibiting NF-κB pathway, thereby lowering apoptosis. Thus, the findings provide new insight into the development of new agents for the treatment of diabetic cardiomyopathy

Diagenesis of the first member of Canglangpu Formation of the Cambrian Terreneuvian in northern part of the central Sichuan Basin and its influence on porosity

In this paper, taking the first Member of the Canglangpu Formation of the Cambrian Terreneuvian in the northern central Sichuan Basin as an example, the diagenesis and its influence on porosity are systemically studied based on the observations and identifications of cores, casts and cathodoluminescence thin sections. The results show that the rock types of the first member of Canglangpu Formation are various, including mixed rocks, carbonate rocks and clastic rocks. The specific lithology is dominated by sand-bearing oolitic dolomite, sandy oolitic dolomite, sparry oolotic dolomite and fine-grained detrital sandstone. At the same time, the Cang 1 Member has experienced five types of diagenetic environments, including seawater, meteoric water, evaporative seawater, shallow burial, and medium-deep burial diagenetic environments. Moreover, the main diagenetic processes under different diagenetic environments include cementation, dissolution, compaction, chemical compaction, dolomitization and structural fractures. According to the analysis, fabric-selective dissolution in meteoric water diagenetic environment, dolomitization in evaporative seawater environment, and non-fabric-selective dissolution, dolomitization and structural fractures in buried diagenetic environment are beneficial to the development of pores. However, cementation, compaction and chemical compaction in medium and deep burial environments, are unfavorable for the development of pores